Active-TwoActiveTwo is a powerful high-resolution biosignal acquisition system that incorporates some revolutionary concepts.  Active electrode technology is just one of the significant innovations in the ActiveTwo system.  By placing active electronics within millimeters of the actual electrode contact, ActiveTwo virtually eliminates the need to prepare the scalp before applying electrodes.  This can cut measurement preparation time by an estimated 15 -30 minutes for most laboratories!

ActiveTwo can also be equipped with additional sensors for respiration, skin conductance, temperature, plethysmograph (pulse) and other parameters.  An optional isolated analog input box makes it possible to acquire almost any type of signal synchronously with the signals sampled by the ActiveTwo A/D box.

As an added benefit, ActiveTwo comes with powerful data acquisition software developed in National Instruments’ LabView.  We provide the compiled software so you do not need to own LabView, and you do not need to be a programmer to operate the system.  For those laboratories with programming resources, the source code is provided so that you can add any special features that you may need.

Each ActiveTwo system is built upon a basic set of items known as the Base System.

Base Components:

  • A/D interface box with no amplifier/converter modules (no channels installed)
  • USB 2.0 interface box with USB 2.0 cable
  • Rechargeable battery unit – 2 each
  • Battery charger with A/C adapter
  • ActiView Data Acquisition Software

Typical Additional Components:

  • Amplifier/Converter modules – up to 32 8-channel modules per A/D interface box
  • Active Electrodes – A/D interface can accommodate up to 256 active electrodes in sets of 32 on high-density connectors and/or up to 8 with individual leads and touch proof connectors
  • Head Caps – with electrode holders and position labels
  • Active Electrodes – with individual leads and touch-proof connectors
  • Trigger Interface Cable
  • Optional Sensors – for galvanic skin response, respiration, temperature, or pulse/plethysmograph

Other Options:

  • Custom-configured auxiliary inputs on the A/D interface box.  These inputs are appropriate for use with battery-powered or self-powered signal sources such as a condenser microphone or a photocell.
  • Analog input box with up to 16 bipolar / 32 monopolar channels and fiber-optic coupling to main A/D interface box

You May Also Need:

  • Consumable supplies
  • Post-processing software
  • Electrode position measurement hardware/software
  • Stimulus delivery software
  • Behavioral response measurement hardware
  • Installation and training

In addition, you will need computers, monitors and interface cables/devices to streamline operation between operator area and subject chamber.  We find that most customers prefer to source these items through their normal channels.  If you prefer to have us provide these items, we can do so if it is more convenient for you.

FAQ's

PowerMAG TMS (6)

Maybe.  There is no way the EEG system can harm the TMS system, but there are some TMS systems that are essentially useless with some EEG systems.  You need a a suitable combination of features in each to be successful at all in using TMS with EEG.

Desirable attributes:

  • Coils designed specifically for use with EEG will have a cable that exits the coil tangential to the head surface so that the coil does not pass close by EEG electrodes and cables.
  • A coil to be used with EEG should be passively cooled, since active cooling by means of a fan will induce electromagnetic interference in the EEG.
  • The TMS recharge mechanism should be designed to avoid inducing electromagnetic artifacts in the EEG.
  • The TMS system should be shielded so that no more than 3 milligauss of electromagnetic interference from the TMS system’s power supply reaches the electrodes and cables.
  • The TMS system should be able to produce a TMS pulse in response to an input trigger with a low and predictable latency.  Long, but especially unpredictable latency in responding to an input trigger will result in TMS artifacts that are difficult to impossible to remove from the EEG.

Aside from attributes of the TMS system, there are also important considerations regarding the EEG system in this relationship. See the other FAQ entry on that topic.

No.  There are a few special attributes that are required and others that are desirable.

Required attributes:

  • Inputs should be protected so that they are not damaged by the TMS pulse
  • Frequency response on all channels should be from DC on the low end, since AC coupled inputs will “ring” when presented with a large voltage transient like the TMS artifact

Desirable attributes:

  • Electrodes should have a low-profile so that the TMS coil can be placed as near the head as possible, maximizing penetration depth and current delivery
  • It is important for the EEG system to be able to trigger the TMS system at precisely the same phase with respect to the EEG samples each time a stimulus is delivered.  This will improve the performance of artifact removal algorithms

Aside from these attributes of the EEG system, there are also important considerations regarding the TMS system in this relationship. See the other FAQ entry on that topic.

You may perform a wide variety of protocols using the PowerMAG system; ppTMS, rTMS, TBS, and even Quattro pulse. Please refer to the following chart to determine which platform is most appropriate for your research.

Category: PowerMAG TMS

The coils used with the PowerMAG system are in fact passively cooled, they utilize quality copper windings with excellent heat dispersion properties. The coils are then placed within a wax like medium that further enhances heat dissipation, as the coil heats up the internal medium changes to a liquid state effectively “absorbing” much of the heat. This is often desired over coils that require additional components for cooling (e.g. fans, pumps, and plumbing), and are considered more robust from an engineering perspective. Additionally there is no maintenance required for our passively cooled coils, nor is there any pre-defined factory set limit to the life of the coil in terms of number of pulses, nor age.

Category: PowerMAG TMS

This really comes down to the properties of the coil utilized. The two main style of stim coils used within the TMS field are figure 8 and round, with figure 8 often being preferred for focal targeting. Typically with the figure 8 coil you would get greatest stimulation at a depth of roughly 2- 2.5cm, with a round style you may achieve a bit more penetration ~2.5-3cm.

Category: PowerMAG TMS

Excellent question! PowerMAG is strictly for research purposes, meaning there is no FDA approval on the device, thus it may not be used for the diagnosis or treatment of any pathology. Clinical research is still possible, however must follow the strict adherence to the current guidelines imposed. Chances are, if you have an IRB protocol, then you can use the PowerMAG system for your research.

For an FDA approved TMS solution for use in treatment protocols, you may find the Mag and More Apollo TMS Therapy System of interest.

Category: PowerMAG TMS

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Citations

This is a sample list of some recent publications.  For more, visit Google Scholar.