About EMSE
Software to measure, describe and visualize human brain dynamics.
EMSE Suite is advanced, powerful, and easy-to-use software to measure, describe, and visualize human brain dynamics, used worldwide for research in neuroscience, neurotechnology, and clinical neurophysiology. We specialize in multimodal source estimation techniques, enabling the researcher to combine EEG and MRI datasets to better answer where things are happening in the brain, and when things change.
Conventional neuroimaging (for example magnetic resonance imaging, or MRI) can answer the where question, but not the when question. Electroencephalography (EEG) and the closely allied Event-Related Potentials (ERP’s) can tell you when something happened with an accuracy of thousandths of a second, but isn’t very good at the where questions. EMSE combines MRI and EEG to answer both when and where in a way that neither method can answer alone. We call this process multimodal dynamic functional brain imaging or source estimation.
EMSE Suite is offered as a scalable desktop application at three levels with EMSE Locator offered as an optional add-on module that can be used with any of the EMSE Suite license levels.
- EMSE Data Editor+ is a tool for sensor space preprocessing of EEG and MEG raw data (with task-related events and intervals) for time, frequency, and time-frequency analyses, including nonparametric statistical tests.
- EMSE Source Standard performs various inverse solutions using FEM standard head models (in MNI space) for researchers without individual MRIs.
- EMSE Source MRI constructs individualized BEM and FEM models that map to and from standard MNI space.
- EMSE Locator is ergonomic software to measure electrode locations on the surface of the head of an individual human EEG participant.
EMSE License Levels
EMSE Data Editor +
Home » Products » EMSE » EMSE Data Editor + Data Editor + The EMSE Suite DATA EDITOR + module may be used as a standalone program to view, analyze,…
EMSE Source Standard
Home » Products » EMSE » EMSE Source Standard EMSE Source Standard EMSE Source Standard includes all of the functionality of EMSE Data Editor + as well as the ability…
EMSE Source MRI
Home » Products » EMSE » EMSE Source MRI EMSE Source MRI EMSE Source MRI includes all of the functionality of EMSE Data Editor + as well as the ability…
EMSE Locator
Home » Products » EMSE » EMSE Locator EMSE Locator 2.0 The purpose of Locator is to facilitate the co-registration and integration of electroencephalography (EEG, scalp-measured brain electrical activity) with…
Quick Demo Videos of EMSE Suite Functionality
For a complete list of full-length instructional videos, visit the EMSE Suite playlist.
EMSE FAQs
EMSE EEG / MEG analysis software (9)
Locator Software Installation
Locator is delivered either as a self-contained downloadable installation program or on a USB flash drive, depending on which type of license you purchase. In either case, you will receive an installation program called Locator_Installer.msi that you will need to run as administrator. When you run the installer, you will be presented with a Welcome Screen asking you to confirm that you want to proceed with installation. After you click Next to proceed, you will be asked to accept the Software License Agreement. Finally, on the Confirm Installation screen, you will be asked to reconfirm that you wish to install the software. After confirming, you will see the Installing Locator screen indicating that Locator is being installed.
After the process has completed, you will see an acknowledgement that installation has been completed.
If you want to uninstall Locator, you must use the Add or Remove Programs tool found in Windows Settings > Apps > Installed Apps.

The installation process will place an icon on the current user’s Windows desktop to access the program. If you click the Windows Start button or press the Windows key on your keyboard and then type Locator, you will see a link to launch the Locator app.
| Locator launch button shown when you type Locator from Windows Start menu. |
Folders Created by the Installation Procedure
| Folders | Contents |
| C:\Program Files\Cortech Solutions\Digitizer | The Locator application (.exe) and its required DLLs and other resources |
| C:\ProgramData\Cortech Solutions\Locator\head_model | The New York Head in various 3D file formats |
| C:\ProgramData\Cortech Solutions\Locator\probe_template | A selection of pre-built electrode probe files that have been coregistered with the New York Head |
| C:\ProgramData\Cortech Solutions\Locator\sequence | A selection of pre-built electrode digitization sequences |
| C:\ProgramData\Cortech Solutions\Locator\Sound\female voice | Pre-recorded sound files in a female voice for each of the electrodes in the provided probe and sequence files |
| C:\ProgramData\Cortech Solutions\Locator\Sound\male voice | Pre-recorded sound files in a male voice for each of the electrodes in the provided probe and sequence files |
License Activation
The Locator software license can be activated in one of two ways:
Activate USB License

Requirements:
- Installed HASP USB driver (required before plugging in the USB dongle)
- Plug in the HASP USB license key (with red LED illuminated)
- Locator.hkey file (USB hardlock license activation file)
Steps:
- Install the HASP USB driver.
- The HASP USB license key driver will be provided with the Locator installation media, whether you download the installer or we provide a USB flash drive containing the media. Double-click on the file install_HASP.bat to install the HASP driver. Running haspdinst.exe directly WILL NOT install the driver. The file Haspdinst.exe will be provided with the Locator installation media, whether you download the installer or we provide a USB flash drive containing the media.
- This must be done before plugging in the USB license key.
- The HASP USB license key driver will be provided with the Locator installation media, whether you download the installer or we provide a USB flash drive containing the media. Double-click on the file install_HASP.bat to install the HASP driver. Running haspdinst.exe directly WILL NOT install the driver. The file Haspdinst.exe will be provided with the Locator installation media, whether you download the installer or we provide a USB flash drive containing the media.
- Insert the HASP USB license key into a USB port.
- If the driver is installed, the red LED on the USB key should illuminate.
- If the driver is installed, the red LED on the USB key should illuminate.
- Click “Activate USB License.”
- A file dialog will open. Navigate to the location of your Locator.hkey file.
- If you purchased a perpetual EMSE Locator 2.0 license (model SA-EM-MOLO, dated after August 1, 2025): The file is on the USB flash drive included with your package.
- If you upgraded to Locator 2.0 from an earlier version: The file was sent via email. Save it to your computer before proceeding.
- If you purchased a perpetual EMSE Locator 2.0 license (model SA-EM-MOLO, dated after August 1, 2025): The file is on the USB flash drive included with your package.
- Select the Locator.hkey file → Click OK.
- If successful, a notification will confirm activation. You can now use Locator.
Activate Machine License
The machine license binds the license to the computer where the software is installed (no dongle required).
If you purchased a one-year Machine License (model SA-EM-MOSLO), you will activate it using the 3-Step Machine License procedure. This process begins with the invoice (sales order) number from your purchase.
If you ordered online, you should have received an email with your invoice/sales order number and activation instructions.
Selecting this option in Locator 2.0 opens the 3-Step License Activation dialog.

In the 3-Step License Activation dialog:
- Step 1: Enter the Order Code provided by Cortech Solutions in the first field and click Apply.
- Step 2: A Machine Code will appear in the second field

Next, you will need to login at cortechsolutions.com using the same email address / account under which you purchased the software, and then visit the page cortechsolutions.com/emse-machine-license/ where you will see a link to the licensing page:

Clicking the Access Customer Care Portal link will take you to the Machine License activation page:

Enter the sales order / invoice number we provided, and the Machine Code that the 3-step licensing dialog displayed in the Machine Code field. The form will then provide you with an Activation code that you can paste into the Activation Code field in the 3-Step License Activation dialog in Locator.
- Step 3: Paste the Activation code displayed on the form to the Activation Code field in the dialog, and then click Apply.
If all of the steps were completed correctly, the “Activated modules: Locator” message appears, click OK to start using the software.
If you encounter any problems with this procedure, please contact EMSEsupport@cortechsolutions.com with your sales order / invoice number, the email address of the purchaser, and a description of the problem or error message you are experiencing.
License Status
Selecting this menu item will display a dialog in which the current status of your license will be displayed. This will let you know whether your license is active or inactive and how long you have before it expires.
Help > About Locator
This option will display a dialog in which the version number and build number of the installed Locator software will be displayed. This information may be requested if you report a software bug or a licensing issue.
YouTube Video Covering Installation and License Activation
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EMSE’s Development Plan emerges from three main streams. First, we listen to your needs and requests (e.g., you might show us what you want during a remote technical/scientific support session). Second, we periodically update and upgrade existing features (e.g., update of boundary element head models; upgrade from 32-bit to 64-bit code). Third, we’re envisioning an integrative role for EMSE in the larger field of human neurophysiology and neuroimaging, so that: (a) EMSE shall perform live analysis and automatic archiving during data acquisition; and (b) EMSE shall cooperate with other tools in an ecosystem based on FAIR (Findable, Accessible, Interoperable, Reusable) principles.
EMSE is developed by Cortech Solutions. We are an agile team with more than 50 years combined experience in the field. Principal developers are Mark Pflieger and Li Gao, who have worked on the EMSE project for 17+ years and 21+ years, respectively. Richard Greenblatt initiated the EMSE project in the early 1990s with roots from the MEG community.
No, EMSE is modular. The ERP Bundle (Data Editor plus Visualizer) is a powerful and affordable package for discovering and confirming space-time-frequency phenomena at the scalp level, with integrated nonparametric statistics. The Basic Source Estimation Bundle adds the Source Estimator module for brain level modeling. The Locator module digitizes electrode locations, which may be co-registered with MRI using MR Viewer. The Image Processor module can segment head tissues for constructing individual cortex and volume conductor models.
If EEG/ERP is a new addition to your lab, you can use EMSE to rapidly master all of the steps that can lead you to discover and visualize new phenomena in your experimental data. Have you already identified phenomena at the scalp? Then you can use source reconstruction and source signal estimation tools in EMSE to understand where and when these phenomena arise in the cortex. Going further, if you have participant MRIs, then you can use EMSE to sort out meaningful individual differences from incidental differences that derive from personal cortical folding patterns. In all cases, we can remotely assist with the steps.
EMSE is great for helping you, first, to identify robust space-time-frequency phenomena in your EEG or MEG data, and then to interpret those phenomena in brain space by constructing source models, by estimating regional activity, and by deriving inter-regional connectivities. EMSE can use MRI data to construct realistic volume conductor models of the head. Importantly, EMSE reproducibly automates and documents your analysis workflows, including: (a) signal processing pipelines; (b) experimental event logic pipelines; (c) event-related component measurements; and (d) nonparametric statistical hypothesis testing. EMSE is a professionally supported Windows application. We can remotely assist your data analysis process.
EMSE News
Announcing the Release of EMSE Locator 2.0
We are pleased to announce the release of a new version of our popular EMSE Locator software module. Locator 2.0 extends the tradition of easy-to-use software established by the original…
EMSE Suite 6.4 Now Fully 64-Bit: Virtually Unlimited Addressable Memory for Larger Datasets
EMSE 6.4 is the current stable release of our flagship EEG and MEG signal processing and source estimation software platform.
EMSE Scripting Engine Service
We are pleased to announce the EMSE Scripting Engine, new functionality built-into the latest release of EMSE Suite that allows us to configure fully automated analyses of your experimental EEG…



