EMSE is a suite of advanced, powerful, and useable software tools to measure, describe, and visualize human brain dynamics, for use by researchers and clinicians worldwide. We specialize in multimodal source estimation techniques, enabling the researcher to combine EEG and MRI datasets to better answer where things are happening in the brain, and when things change.

Conventional neuroimaging (for example magnetic resonance imaging, or MRI) can answer the where question, but not the when question. Electroencephalography (EEG) and the closely allied Event-Related Potentials (ERP’s) can tell you when something happened with an accuracy of thousandths of a second, but isn’t very good at the where questions. EMSE combines MRI and EEG to answer both when and where in a way that neither method can answer alone. We call this process multimodal dynamic functional brain imaging or source estimation.

EMSE Modules



When used together with Polhemus™ digitizing hardware, LOCATOR allows you to measure accurately electrode locations an external head shape in 3 dimensions. These data may then be used for MRI coregistration and more accurate source estimation. LOCATOR currently supports three Polhemus products: ISOTRAK, FASTRAK, and PATRIOT.


Data Editor

The EMSE Suite DATA EDITOR module may be used as a stand-alone program to view, analyze, filter and transform EEG and MEG time series data, and to select intervals or events for further analysis, including topographic mapping, spatial components analysis and wavelet decomposition.


Source Estimator

EMSE Suite SOURCE ESTIMATOR module may be used for discrete or distributed dipole source analysis from EEG or MEG data which has been provided by the DATA EDITOR module. Three shell spherical models or realistic head models (using data from the IMAGE PROCESSOR module) may be used for field calculations. Source estimates may be output to MR VIEWER for MRI overlay.


MR Viewer

MR VIEWER displays magnetic resonance and other images, with specialized features designed for the overlay of electromagnetic source estimation and other functional imaging data. Seeded dipoles may be obtained (e.g. from fMRI data) for use with SOURCE ESTIMATOR.


Image Processor

Starting with a volumetric dataset from the MR VIEWER base module, IMAGE PROCESSOR tools support segmentation, boundary mesh generation, and cortical unfolding. The output may be made available to VISUALIZER for 3D rendering, or to SOURCE ESTIMATOR for realistic headshape modeling and cortical surface restriction.



Use VISUALIZER to obtain and view 3D rendered images, combining data from several modalities, including topographic mapping, MRI data and electromagnetic source analysis.